It’s In the News, a look at the top stories and headlines from the diabetes community happening now. Top stories this week: a look at how weight loss might lower cancer risk in people with type 2, a new study that says BG spikes are good(?!), Modular Medical submits a new insulin pump the FDA, another look at COVID-19’s effects on people with diabetes, a marathoner with type 1 heads to the last trial for this summer’s Olympics, and more!

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Hello and welcome to Diabetes Connections In the News! I’m Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now.

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In the news is brought to you by Edgepark simplify your diabetes journey with Edgepark

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Our top story this week…

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A weight loss intervention in people with type 2 diabetes was found to alter levels of cancer-related proteins. The study, published in eBioMedicine, is the first to show that weight loss in people recently diagnosed with diabetes can change the levels of cancer-related chemicals circulating in the blood.

Previous studies have found that having increased body weight alters the levels of circulating proteins with a known link to cancer. Motivated by these findings, researchers from Bristol Medical School collaborated with colleagues from the universities of Glasgow and Newcastle who led the DiRECT trial. They sought to evaluate whether the benefits of weight loss in people with type 2 diabetes also impacts their risk of developing cancer.

Nine cancer-related proteins in blood samples were found to be changed by the weight loss intervention compared with the control group who had received standard care for diabetes treatment.

https://medicalxpress.com/news/2024-01-weight-loss-intervention-people-diabetes.html

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While a lot is being studied about the factors that trigger the onset of chronic diseases like diabetes and cholesterol, a new study has shed light on an uncommon risk factor. A study done by researchers at the Harvard Pilgrim Health Care Institute has found that the milestones in a female’s reproductive years could be the risk factors for metabolic dysfunction.

This was published in Cell Metabolism.

These reproductive risk factors include early age of first menstruation, menstrual irregularity, the development of polycystic ovary syndrome (PCOS), high weight change in pregnancy, abnormal blood sugar and lipid levels during pregnancy and the severity and timing of menopausal symptoms.

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/age-of-first-menstruation-among-risk-factors-for-diabetes-cholesterol-in-females-finds-study/articleshow/107249372.cms?from=mdr

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Dexcom has submitted its new CGM to the FDA – this is intended for people with diabetes who do not require insulin. Called Stelo, it will last for 15 days and it won’t have the same alarms as the previous Dexcom models. Pricing said to be in line with the Abbott Free Style Libre systems.

https://www.drugtopics.com/view/dexcom-submits-new-cgm-for-non-insulin-type-2-diabetes-for-fda-clearance

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This study is one to watch.. researchers at Sinai Health have discovered important insights into the link between post-meal insulin levels and long-term cardiac and metabolic well-being. This study challenges the prevailing belief that an insulin spike after eating is a bad thing.

These doctors say it could be an indicator of good health to come.

The team reported their findings in the online journal eClinicalMedicine, published by the Lancet group.

These researchers say In the long run, higher corrected insulin response levels were linked with better beta-cell function and lower glucose levels.

Overturning Old Myths: New Research Indicates That Insulin Spike After Eating Is Actually a Good Thing

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For people with diabetes, disruption from the COVID-19 pandemic led to higher rates of death and other adverse outcomes, particularly diabetic ketoacidosis (DKA) in children, new research found.

 

The data came from what was believed to be the first systematic review of evidence related to the clinical impact of the disruptions caused by the COVID-19 pandemic and delays in seeking care among people with diabetes, rather than illness from the virus itself. The review was commissioned by the World Health Organization (WHO) and included a total of 138 studies.

While there were no differences in overall amputations or DKA in adults, there were significantly higher rates of DKA hospitalizations in children and adolescents, both with new-onset and preexisting type 1 diabetes.

https://www.medscape.com/viewarticle/pandemic-disruption-adversely-affected-people-diabetes-2024a10001wt

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Disordered eating BBC

https://www.bbc.com/news/health-68057324

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A new insulin pump is before the FDA – this is from San Diego-based Modular Medical. It’s let by Paul DiPerna who founded Tandem Diabetes Care.  A news release says:

Modular Medical designed the 90-day MODD1 with new microfluidics technology to allow for the low-cost pumping of insulin. Its new intuitive design makes the product simple to use and easier to prescribe.

 

The pump has a reservoir size of 300 units/3mL. Users can monitor the pump activity with their cell phone and do not require an external controller. The pump uses a provided, single-use, disposable battery.

Modular Medical submits next-gen insulin pump for FDA clearance

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Dexcom CIQ | Garmin

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Commercial

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A new CGM from Roche? What do we know?

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The last qualifier for the Women’ Marathon at the Summer Olympics is this weekend and there’s a runner with type 1 hoping to make the cut. Sofie Schunk

Was diagnosed with type 1 while in college, where she played soccer and track and field. The Albuquerque native has passed two qualifying Olympic trials for the marathon. In both runs, she set personal records.

The top three runners, as well as three alternatives, will represent Team USA in Paris.

The qualifying race is set for Saturday, Feb. 3. in Orlando.

The 2024 Summer Games in Paris begins Friday, July 26.

 

https://www.runnersworld.com/runners-stories/a46552797/sofie-schunk-diabetes-olympic-marathon-trials/

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